What is Capacity Building Assistance (CBA)?

Diffusion of Effective Behavioral Interventions (DEBI) for HIV Prevention

What is HIV and why do I need to know about it?


What is syphilis?

What is Capacity Building Assistance (CBA)?

Capacity Building Assistance (CBA) focuses on maintaining and increasing the infrastructural systems and resources necessary to support interventions, and enhance the abilities of key personnel to plan and implement interventions and activities. Capacity building focuses on the development of core competencies, or skills of individuals in both organizations and communities to more effectively deliver HIV prevention services, and to sustain and support infrastructure for HIV programs.

What is MPIC~APIN?

The Midwestern Prevention Intervention Center of the African American Prevention Intervention Network (MPIC~APIN) is a project designed to assist community based organizations (CBOs) in the Midwestern Region of the United states with adaptation, implementation, quality assurance and evaluation of effective HIV prevention interventions.

The geographic region serviced by MPIC~APIN is: CO, IA, KS, MO, MT, NE, S. Dakota, N. Dakota, UT and WY.

How can Capacity Building Assistance help you to better serve your community?

  • Through jointly developing a comprehensive capacity building assistance needs assessment that reflects your prioritized needs.

  • Through stronger community based organizations representative of African Americans in science based prevention efforts against HIV disease.

  • Through behavioral science and intervention effectiveness that are essential elements in building the capacity of organizations to lead the fight against HIV disease.
How Do You Access CBA Services?
  • Contact your CDC Project Officer.
  • Your CDC Project Officer will deliver your request to the CBA Coordinator.
  • The CBA Coordinator will assign your request to the appropriate provider(s).
  • A CBA provider will contact your organization directly to assess your needs.
  • Community stakeholders, indirectly or non-CDC funded health departments and community based organizations should contact the MPIC Coordinator, E. Tyronne Howze at (314) 421-9600 or by e-mail at ET Howze@aol.com

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Diffusion of Effective Behavioral Interventions (DEBI)for HIV Prevention

The Diffusion of Effective Behavioral Interventions Project (DEBI) is a national-level strategy to provide high quality training and on-going technical assistance on selected evidence-based HIV/STD prevention interventions to state and community HIV/STD program staff.

The interventions have been proven effective through research studies that showed positive behavioral (e.g., use of condoms; reduction in number of partners) and/or health outcomes (e.g., reduction in the number of new STD infections). Studies employed rigorous research designs, with both intervention and control groups, so that the positive outcomes could be attributed to the interventions. With input from the researchers, the materials necessary to implement the interventions have been packaged into user-friendly kits. With the appropriate training and intervention package, service providers can increase their opportunities to conduct effective HIV/STD prevention programs in their communities.

Why Community and Group-Level interventions?
Community- and group-level interventions, compared to individual-level, have the potential to reach large numbers of the population and reach individuals at high risk who might not voluntarily seek prevention information or services. They are also more cost-effective.

The interventions in the Compendium have been identified by CDC's HIV/AIDS Prevention Research Synthesis Project (PRS) as having used rigorous study methods and demonstrated evidence of effectiveness in reducing sex- and drug-related risk behaviors and/or improving health outcomes.

Overview of DEBI Interventions

Healthy Relationships
Healthy Relationships is a five-session, small-group intervention for men and women living with HIV/AIDS. It is based on Social Cognitive Theory and focuses on developing skills and building self-efficacy and positive expectations about new behaviors through modeling behaviors and practicing new skills. Decision-making and problem-solving skills are developed to enable participants to make informed and safe decisions about disclosure and behavior. The sessions create a context where people can interact, examine their risks, develop skills to reduce their risks, and receive feedback from others.

Holistic Harm Reduction Program (HHRP)
The Holistic Harm Reduction Program (HHRP) is a 12-session, manual-guided, group level program to reduce harm, promote health, and improve quality of life. The primary goal of HHRP is to provide group members with the resources (i.e., knowledge, motivation, and skills) they need to make choices that reduce harm to themselves and others.

Many Men, Many Voices
Many Men, Many Voices (3MV) is a six- or seven-session, group level STD/HIV prevention intervention for gay men of color. The intervention addresses behavioral influencing factors specific to gay men of color, including cultural/social norms, sexual relationship dynamics, and the social influences of racism and homophobia.

Mpowerment
This community-level intervention for young men who have sex with men uses a combination of informal and formal outreach, discussion groups, creation of safe spaces, social opportunities, and social marketing to reach a broad range of young gay men with HIV prevention, safer sex, and risk reduction messages.

Popular Opinion Leader (POL)
This 4 session community-level intervention involves identifying, enlisting, and training key opinion leaders to encourage safer sexual norms and behaviors within their social networks through risk-reduction conversations.

Community PROMISE (Peers Reaching Out and Modeling Intervention Strategies)
This community-level intervention is based on several behavior change theories. A community assessment process is conducted, peer advocates are recruited and trained from the target population, role model stories are written from interviews with the target population, and these stories are distributed along with other risk reduction materials to target audiences to help people move toward safer sex or risk reduction practices. The intervention can be adapted for various population groups (IDUs, MSM, sex workers, Native Americans, and youth at high risk).

Real AIDS Prevention Project (RAPP)
A community mobilization program, designed to reduce risk for HIV and unintended pregnancy among women in communities at high risk by increasing condom use. This intervention relies on peer-led activities, including: outreach/one-on-one brief conversations with brochures, referrals, and condom distribution; small group safer sex discussions and presentations. There is also peer interaction with community businesses that participate in media campaigns with distribution of role model stories and prevention and health information newsletters and brochures. RAPP is based on the transtheoretical model of behavior change.


SISTA (Sisters Informing Sisters About Topics on AIDS)
This group-level, gender- and culturally- relevant intervention is designed to increase condom use with African American women. Five peer-led group sessions are conducted that focus on ethnic and gender pride, HIV knowledge, and skills training around sexual risk reduction behaviors and decision making. The intervention is based on Social Learning theory as well as the theory of Gender and Power.

Street Smart
A multi-session, skills-building program to help runaway and homeless youth practice safer sexual behaviors and reduce substance use. Sessions address improving youths' social skills, assertiveness and coping through exercises on problem solving, identifying triggers, and reducing harmful behaviors. Agency staff also provide individual counseling and trips to community health providers.

Teens Linked to Care (TLC)
TLC is an effective intervention for young people living with HIV. TLC is delivered in small groups using cognitive-behavioral strategies to change behavior. Young people meet regularly to provide social support, learn and practice new skills, and socialize. This program helps young people identify ways to improve the quality of their lives by setting new habits and daily social routines. They set goals regarding their health, sexual relationships, drug use, and daily peace.

VOICES/VOCES (Video Opportunities for Innovative Condom Education & Safer Sex)
A group-level, single-session video-based intervention designed to increase condom use among heterosexual African American and Latino men and women who visit STD clinics. Participants, grouped by gender and ethnicity, view an English or Spanish video on HIV risk behaviors and condom use and take part in a facilitated discussion.

Safety Counts
Safety Counts is an HIV prevention intervention for active injection drug and crack cocaine users aimed at reducing both high-risk drug use and sexual behaviors. It is a behaviorally focused, seven-session intervention, which includes both structured and unstructured psycho-educational activities in-group and individual settings.

Fundamentals of HIV Prevention Counseling
This course is designed to develop a counselor’s proficiency and enhance the abilities of counselors in HIV testing contexts as well as other settings to provide effective HIV prevention counseling.

HIV Prevention Counseling: Addressing Issues of Clients Who Test Positive
This course is designed to give voice to the considerable challenges involved in counseling clients who receive a diagnosis of a highly stigmatized and life-threatening disease that is epidemic. There is a brief review of counseling, behavior change principles and strategies for taking action and a discussion of the often competing expectations placed on this work helps to define some reasonable parameters of effective counseling of HIV-positive clients.

Partner Counseling and Referral Services (PCRS)
This course id designed to enhance a counselor’s ability to: a) provide services to HIV-infected persons and their sex and needle-sharing partners so they can reduce their risk for infection or, if already infected, can prevent transmission to others and b) help partners gain earlier access to individualized counseling, HIV testing, medical evaluation, treatment, and other prevention and support services.


Go to http://www.effectiveinterventions.org for more information on the DEBI Project.


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What is HIV and why do I need to know about it?


AIDS - acquired Immunodeficiency syndrome - is caused by a virus called HIV, the human immunodeficiency virus.

AIDS was first seen in the United States in 1981 and is now a major problem all over the world. We have all heard much about AIDS in the news over the years, and the number of deaths it has caused worldwide, particularly in areas hardest hit by the disease like Africa. Many myths have been spread about AIDS and it is important for every person to know the facts about HIV and AIDS.

HIV attacks, kills, and damages the cells in the body's immune system. Our immune system protects our bodies from disease and infection. Over time, HIV weakens a person's immune system, making it hard to fight off infections and certain cancers. People who have AIDS can get very sick with infections that most healthy people can fight off. These are called opportunistic infections (OIs), and can be life threatening. There is no cure for AIDS and while treatments may help some people manage their disease, AIDS is still fatal.

Almost one million Americans are living with HIV infection, one-third of who do not even know that they have HIV. HIV has hit African American and Hispanic women the hardest. While they make up less than 25 percent of the people in the U.S., they account for more than 77 percent of AIDS cases in women.

How does a person become infected with HIV? Is it true that a pregnant or breastfeeding woman can give HIV to her baby?


HIV is found in body fluids - blood, semen (the fluid a man releases from his penis when he becomes sexually aroused or has an orgasm), vaginal fluid (fluid or secretions from a woman's vagina or birth canal), and breast milk.

HIV can enter the body:

  • By having unprotected (meaning not using a condom) vaginal, anal, or oral sex with a person living with HIV. HIV can enter the body through the lining of the vagina (birth canal), vulva ("lips" or opening to the vagina), penis, rectum, or mouth during sex. Anal sex without a condom is very risky because the rectum does not stretch easily (like the vagina), making it more likely to tear and bleed, and making it easier to become infected with HIV.
  • By sharing needles, syringes, and other drug injection equipment that has a small amount of blood on it from someone who has HIV. This refers to both equipment used to inject illegal drugs (like heroin and cocaine) and legal drugs (like steroids, insulin, and vitamins). A person can also get HIV from using tattoo or body piercing equipment and razors that have blood on them from someone who has HIV.
  • During pregnancy, birth, or breastfeeding from a mother who has HIV to her baby. During pregnancy, HIV can be passed to the growing fetus through the placenta. HIV can also be passed to the baby during the birth process and through breast milk during breastfeeding. Women who have HIV should not breastfeed their babies. An option for a mother who has HIV could be donor milk from a milk bank or infant formula. Call the Mother's Milk Bank, at (919) 350-8599 for help.

    About 25 to 33 percent of all pregnant women who don't take the drug zidovudine (AZT) during pregnancy will pass HIV to their babies. Taking AZT while pregnant and having a cesarean, or C-section, delivery drops a woman's chances of passing HIV to her baby to 1 percent.

  • Through contact with infected blood. Before donated blood was tested for HIV and before heat-treating techniques to kill HIV in blood products were introduced, a person could get HIV from transfusions of HIV infected blood or blood products. Today in the U.S., because all blood is screened for HIV, the risk of getting HIV from blood transfusions is very small. But, some countries don't test donated blood for HIV.
Can you get HIV from doing things like kissing?

HIV has been found in the saliva of people who have HIV. But, it has never been proven that HIV is spread by contact with saliva, such as with kissing. Researchers have also found no proof that HIV is spread through sweat, tears, urine, or feces.
There have been many studies of families of people who have HIV. All have shown very clearly that HIV is not spread through casual contact, such as sharing eating utensils, towels and bedding, swimming pools, telephones, or toilet seats. HIV is not spread by biting insects such as mosquitoes, fleas, or bedbugs.

What are the signs of HIV infection? Do women and men have the same symptoms?

Many people have no symptoms when they first become infected with HIV. But some people get a flu-like illness within a month or two after being exposed to the virus. The flu-like symptoms - fever, headache, fatigue, swollen lymph nodes (immune system glands in the neck and groin) - often go away within a week. During this time, HIV is present in large amounts in semen and vaginal fluids and it is very easy to pass the infection to another person.

All people who have HIV go through what is called an asymptomatic period of infection. This means that a person lives symptom free for a period of time. But, during this time they can still pass the infection to another person. The asymptomatic period varies greatly from person to person. Some people may begin to have symptoms within a few months, while others may be symptom free for 10 years or more.

HIV is active inside a person's body, even when no symptoms are present. The virus multiplies, or makes more virus, killing more and more cells of the immune system that fight infection (called CD4 and T cells). This process weakens a person's immune system over time. For many people, the first symptom they notice is large lymph nodes (swollen glands) that may be enlarged for more than 3 months. Other symptoms often felt months to years before the onset of AIDS include:

  • Lack of energy or fatigue
  • Weight loss.
  • Frequent low-grade fevers and night sweats.
  • Frequent yeast infections (in the mouth). .
  • Skin rashes or flaky skin that is hard to get rid of.
  • Short-term memory loss.
Women who have HIV can also have other symptoms that happen more often, may not respond to treatment, and can be harder to cure including:
  • Vaginal yeast infections.
  • Other vaginal infections such as bacterial vaginosis and common STDs like gonorrhea, chlamydia, and trichomoniasis.
  • Human papillomavirus (HPV) infections that cause genital warts and can lead to cervical cancer.
  • Pelvic Inflammatory disease (PID), or infection of a woman's reproductive organs.
  • Menstrual cycle changes, such as not having periods.
What is AIDS?

AIDS refers to the most advanced stages of HIV infection. The Centers for Disease Control and Prevention defines AIDS as being infected with HIV and having fewer than 200 CD4 and T cells per cubic millimeter of blood. (Healthy adults have CD4 and T cell counts of 1,000 or more). AIDS also includes 26 different conditions, some of which are called opportunistic infections (OIs), or infections that don't usually make a healthy person sick. People who have AIDS can have severe OIs, which can be fatal because their bodies can't fight off certain bacteria, viruses, and other microbes. People with AIDS are also more likely to develop cancers, such as Kaposi's sarcoma, cancer of the cervix (opening to the uterus or womb), and lymphomas (cancers of the immune system).

Symptoms of OIs common in people with AIDS include:
  • Coughing and shortness of breath.
  • Seizures and lack of coordination.
  • Difficult or painful swallowing.
  • Mental symptoms such as confusion and forgetfulness.
  • Severe and persistent diarrhea.
  • Fever.
  • Loss of vision.
  • Nausea, abdominal cramps, and vomiting.
  • Weight loss and extreme fatigue.
  • Severe headaches. Coma.
Is there a test for HIV?

Health care providers can tell if you have HIV by testing your blood to see if you have antibodies (disease-fighting agents) to HIV in your blood. You can't tell if you have HIV antibodies in your blood until 1 to 3 months AFTER you become infected. And, some people can take as long as 6 months to develop antibodies to HIV in their blood. If you think you have been exposed to HIV, it is best to get tested as soon as possible. But, keep in mind that you may have to get another test or have your test repeated in 6 months, to be sure that you have accurate results.

Talk to your health care provider about testing and be sure to have counseling before and after you are tested. Counseling will help you to get the treatment you need if you are HIV positive and will help you to learn how to not pass the infection to others. If you are HIV negative, counseling will help you to stay negative by teaching you what you can do to protect yourself.

The test used for HIV is called an ELISA test. If the ELISA test is positive, it is always followed with a second test to confirm the result. This is called a Western Blot test.

How is HIV infection treated?

In 1981, when AIDS was first seen in the U.S., there were no medicines to fight HIV and few treatments for the opportunistic infections (OIs) and cancers that happen when a person has AIDS. But over the past 20 years, researchers have developed drugs to fight both HIV infection and AIDS OIs and cancers. There is no cure for AIDS and when a person becomes infected with HIV, they will need life long treatment.

The Food and Drug Administration has approved several types of drugs for treating HIV infection. A main goal of treatment is to stop the virus from replicating, or making copies of itself. When the virus is allowed to copy itself, it increases its numbers in a person's body, weakening the immune system. Over time, a person is no longer able to fight off infection and becomes sick.

One group of drugs stops the virus from replicating at an early stage in its life cycle. These drugs are called nucleoside reverse transcriptase, or RT inhibitors. RT inhibitors include zidovudine (AZT), zalcitabine (ddC), dideoxyinosine (ddI), stavudine (d4T) and lamivudine (3TC). These drugs may slow the spread of HIV in the body and delay the onset of OIs.

A second, and more recent, group of drugs are called protease inhibitors. They stop the virus from making copies of itself at a later stage in its life cycle. These drugs include ritonavir (Norvir), saquinivir (Invirase), indinavir (Crixivan), amprevnivir (Agenerase), nelfinavir (Viracept), and Iopinavir (Kaletra).

One challenge to treating HIV infection is persons with HIV can build resistance to these drugs. (Resistance means that the drugs stop working.) Health care providers must use several of these drugs at the same time, called a combination treatment, to stop the virus from replicating. Another challenge is the side effects caused by drug treatment. Side effects can vary widely from person to person. Some people can have severe side effects, including death, and may have to stop or change treatments.

One type of treatment, called highly active antiretroviral therapy, or HAART, has greatly improved the health of many people with AIDS. It can lower the amount of virus in a person's blood to levels so low that it is hard to detect with a blood test. This can mean relief from symptoms and OIs, increasing the quality of life for a person living with AIDS. There are also treatments for OIs and cancers.

What can I do to keep myself from getting HIV?

There is no cure or vaccine for HIV infection and AIDS. It is a life long condition that requires life long treatment. That's why it's so important to keep from getting it in the first place. Here are ways to keep from getting HIV:
  • The best way to prevent HIV or any STD is to practice abstinence (don't have sex). Delaying having sex for the first time is another way to reduce your chances of getting an STD. Studies show that the younger people are when having sex for the first time, the more likely it is that they will get an STD. The risk of getting an STD also becomes greater over time, as the number of a person's sex partners increases.
  • Have a sexual relationship with one partner who doesn't have any STDs, where you are faithful to each other (meaning that you only have sex with each other and no one else).
  • Practice "safer sex." This means protecting yourself with a condom EVERY time you have vaginal, anal, or oral sex. For vaginal sex, use a latex male condom or a female polyurethane condom. For anal sex, use a latex male condom. If needed, use only water based lubricants with male and female condoms. For oral sex, use a dental dam - a device used by dentists, made out of a rubbery material, that you place over the opening to the vagina before having oral sex. If you don't have a dental dam, you can cut an unlubricated male condom open and place it over the opening to the vagina. Even though it may be embarrassing, if you don't know how to use a male or female condom, talk to your health care provider. The biggest reason condoms don't work is because they are not used correctly.
  • Be aware that condoms don't provide complete protection against STDs. But, they do decrease your chances of getting an STD. Know also that other methods of birth control, like birth control pills, shots, implants, or diaphragms don't protect you from STDs. If you use one of these methods, be sure to also use a condom every time you have sex.
  • Limit your number of sexual partners. Your risk of getting HIV increases with the number of partners you have.
  • Don't douche. Douching removes some of the normal bacteria in the vagina that protects you from infection. This can increase your risk for getting HIV.
  • Learn how to talk with your partner about STDs and using condoms. It's up to you to make sure you are protected. The organizations in the "For more information" at the end of this FAQ have tips for talking with your partner. You can also talk with your health care provider about this.
  • When you are sexually active, especially if you have more than one partner, get regular exams for STDs from a health care provider. Tests for STDs can be done during an exam. And, the earlier an STD is found, the easier it is to treat.
  • Learn the common symptoms of HIV and other STDs. Seek medical help right away if you think you may have HIV or another STD.
  • If you are HIV positive and pregnant, you can lower the chances of giving HIV to your baby by taking AZT during pregnancy, labor, and delivery and having your baby take AZT for the first 6 weeks of life.

  • Remember that HIV is a life long disease. When you have HIV, you may have periods of time with no symptoms. But, you can still pass the virus to another person. If you have HIV, you need to tell your sexual partners, so they can be tested

    What is the latest research on HIV and AIDS?


    The National Institutes of Health conducts research on HIV, which includes testing HIV vaccines and new drug treatments and looking at how HIV damages the immune system. Researchers are testing creams, gels, and films (called microbicides) that can be used in the vagina and rectum during sex to prevent HIV infection. They are also looking at the role STDs play in HIV infection, how to help people change their behaviors to keep from getting HIV, and ways for pregnant women to prevent passing HIV to their babies. Women are taking part in AIDS clinical trials across the country. Studies are looking at the signs of HIV infection and AIDS in women and how HIV is passed to babies.

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What is syphilis?

Capacity Building Assistance (CBA) focuses on maintaining and increasing the infrastructural systems and resources necessary to support interventions, and enhance the abilities of key personnel to plan and implement interventions and activities. Capacity building focuses on the development of core competencies, or skills of individuals in both organizations and communities to more effectively deliver HIV prevention services, and to sustain and support infrastructure for HIV programs.

  • Syphilis is a curable infection caused by the bacteria Treponema pallidum
  • The bacteria enter the body through mucous membranes or abraded skin.

  • Once inside the body, syphilis enters the blood stream and attaches to cells, damaging organs over time.
  • There are four stages through which untreated syphilis progresses, each stage with its own unique signs and symptoms:
  • 1. primary
  • 2. secondary
  • 3. latent
  • 4. tertiary (or late)

How common is it?

  • Up until 2000, the reported rate of syphilis in the United States was at its lowest level since reporting began in 1941. In 2001, the number of cases reported increased slightly by a little over 2%.
  • This increase occurred only among men, while the number of cases continued to decline among women and among African American blacks.
  • Most of the reported syphilis cases are in the Southeast of the country, with a higher percentage of cases among African-Americans than whites. In 2001, the South had the highest rate of syphilis, accounting for 56% of reported cases in the US.
  • While rates appear to be improving, syphilis continues to disproportionately affect African Americans, with reported rates 16 times higher for African Americans than for white Americans.
  • Syphilis rates usually increase and decrease in seven-to-ten year cycles, which maybe one reason for the increase.
How can I get syphilis?
Sexual
  • Syphilis transmission can occur when infected lesions come in contact with the soft skin of the mucous membrane found inside the vagina, urethra or with an abrasion during vaginal, oral and anal sex, even if there is no sexual penetration.
  • It is most easily spread during the first stage because symptoms usually go unnoticed.
  • Syphilis can also be contracted from exposure to lesions or syphilitic "warts" during the secondary stage.
  • If "warts" are present, they may easily spread the syphilis bacteria, due to the large amount of virus present.
  • Because symptoms of secondary syphilis can recur, a person who has entered the latency stage of syphilis can still transmit the disease.

  • Nonsexual
  • Because syphilis bacteria are extremely fragile, they cannot be spread during contact with objects such as toilet seats or towels.
  • People, especially health care workers, can be at risk for syphilis if an abrasion or cut on the skin comes into contact with a syphilitic lesion
Mother-to-Child
  • Syphilis can also be transmitted during pregnancy or during childbirth from a mother to her infant.

What are the symptoms of syphilis?
Primary Syphilis:
-Chancre
  • The primary stage of syphilis is usually marked by the appearance of a single sore, known as a chancre, within 10 to 90 days after contact with the bacteria at the site of infection.
  • It is usually appears as a single, painless sore, that is raised or elevated.
  • Chancres may be found:
    - outside the genitals, including the penis, scrotum and vagina

    - inside the vagina or rectum

    - at or around the anus

    - on the lips or in the mouth, though this is not as common.

    - The sore can last from one to five weeks and will go away by itself.

    - The chancre will go away with or without treatment. Without treatment, the person will still have syphilis and can transmit it to others.
Secondary Syphilis
  • The secondary stage of syphilis can develop 17 days to 6 1/2 months after infection.
  • Symptoms can last from 2 to 6 weeks.
  • Symptoms can include:
    - A rough, reddish-brown rash that appears on the palms of your hands or the soles of your feet, which normally does not itch.

    - Rashes on other parts of the body, including the neck, head and torso.

    - Condylomata lata or syphilitic "warts", moist, raised or elevated skin lesions, may be found in the anus or genital area.

    - "Mucous patches," flat, round, grayish-white sores, can appear on the mouth, throat, and cervix.

    - Patchy loss of hair on the head and other parts of the body.

    - A general sense of ill health.
  • Symptoms of secondary syphilis will clear up with or without treatment, but the disease will still be present if untreated. It will then enter into a latent stage, which has no signs or symptoms.
Latent Stage
  • Latent syphilis is defined as the time where there are no signs or symptoms of the disease
  • Develops from two to 30+ years after infection.
  • Because there are no signs or symptoms, the only way to test for infection during the latent period is by blood test.
  • A relapse of secondary syphilis can occur once the disease has entered the latent stage. This normally will happen during the first two years of latency.
Late Stage (Tertiary)
  • Symptoms of late stage or tertiary syphilis can occur 2 to 30+ years after infection.
  • Complications during this stage can include:

  • - Gummas: Small bumps or tumors that can develop on the skin, bones, liver or any other organ.

    - Problems with heart and blood vessels

    - Chronic nervous system disorders, such as blindness, insanity and paralysis
  • If treated during this period, gummas will usually disappear. Though treatment at this phase will cure the disease and stop future damage to the body, it cannot repair or reverse the damage that occurred before treatment.

Congenital Syphilis
A mother infected with syphilis can pass the disease to her unborn child, either during pregnancy or in childbirth. A newborn infected in this manner has congenital syphilis.
  • Early signs generally appear from three to eight weeks after a baby is born.
  • Even though these symptoms develop soon after birth, most cases go unnoticed until late congenital symptoms appear in childhood or adolescence.
  • Late congenital syphilis has similar symptoms to tertiary syphilis in adults, though heart complications rarely occur in cases of congenital syphilis
How can I find out if I have syphilis?
Syphilis can be detected by blood tests, which looks for antibodies, or by testing fluid taken from lesions or swollen lymph nodes, which occur during primary or secondary syphilis. Tests on the lymphatic fluid or lesions look for antigens.

Darkfield Exam
  • This test uses a fluid sample taken from the chancre during primary syphilis or from symptoms that occur during secondary syphilis found in areas such as the vagina (women) or the urethra (men).
  • The sample is then viewed under a microscope.
  • This test can only be done during primary or secondary syphilis, when sores, lesions & warts are present.
Blood Tests
  • There are two types of blood tests used to detect syphilis: nontreponemal and treponemal. These tests can be done in all stages of syphilis.
  • Nontreponemal blood tests are screening tests that look for certain antibodies , but not specifically syphilis antibodies. There are two types of screening test that may be used:

  • - VDRL (Venereal Disease Research Laboratory)

    - or RPR (Rapid Plasma Reagent)
  • If the results for these test come back positive, a more specific treponemal blood test is performed to confirm a positive result. There are two types of confirmatory tests that may be used:

  • - FTA-ABS (Fluorescent Treponemal Antibody Absorption Test)

    - MHA-TP (Microhemagglutination-Treponema Pallidum)
  • There is a possibility of a false positive, particularly if the person tested has had syphilis before. A test may also be a false positive result if you are pregnant, have rheumatoid arthritis, use heroin, or have hepatitis, influenza or pneumonia.
Cerebrospinal Fluid Test
  • Another test uses cerebrospinal (involving the brain and spinal chord) fluid and is usually done if a person has damage to their central nervous system.
Testing in Infants
  • If no signs and symptoms are found at birth, a blood test should be performed every 2 to 3 months on the infant until the test comes back negative. This is because an infant may test positive for syphilis and not be infected until the mother's antibodies, transmitted during pregnancy, clear the infant's body. For more information about testing and treatment of infants, talk with your health care provider, or visit your local health department.
What is the treatment for syphilis?
  • The preferred treatment for syphilis is penicillin. If you are allergic to penicillin, your health care provider can suggest another antibiotic.
  • If you have HIV, tell your health care provider. The antibiotic may not be as effective.
  • Penicillin is the only recommended treatment for pregnant women. If you are pregnant and are allergic to penicillin, talk to your health care provider. He/she can use a process called desensitization that may allow a person to take penicillin.
  • Infants should be checked carefully at birth. Treatment can vary for many reasons. For more information about testing and treatment of infants, talk with your health care provider, or visit your local health department.
Treatment Follow Up
  • Take all medications as directed.
  • All partners should be examined and treated.
  • Do not have sex until you and your partner(s) have been treated and cured.
  • After treatment for primary or secondary syphilis, it is recommended that a person be retested after 6 months, and once again after a year.
  • If you are treated in the latent period, follow up tests are recommended after 6 months, 12 months & again at 24 months.
  • People who are infected with syphilis and also have HIV, should be retested every 3 months for 2 years.
What can I do to reduce my risk of getting syphilis?
  • Abstinence (not having sex).
  • Mutual monogamy (having sex with only one uninfected partner).
  • Latex condoms for vaginal and anal sex. Condoms may protect the penis or vagina from infection, but do not protect from contact with other areas such as the scrotum or anal area.
  • Several barrier methods can be used to reduce the risk of transmission of syphilis during oral sex. A non-lubricated condom can be used for mouth-to-penis contact. Household plastic wrap, a dental dam, or a latex condom cut-up and opened flat can reduce the risk of transmission during mouth-to-vulva/vagina or oral-anal (rimming) contact.
Why worry?
If you do not get treated, syphilis can cause blindness, paralysis, and problems with your bones and internal organs, including your heart.

Do I need to talk to my partner about syphilis?

Yes. Telling a partner can be hard, but keep in mind that some people with syphilis don't know they have it. It's important that you talk to your partner as soon as possible so she or he can get treatment. Also, it is possible to pass syphilis back and forth, so if you get treated and your partner doesn't, you may get infected again.

Should I talk to my health care provider about syphilis?
Yes. Because syphilis often does not have symptoms, you may need to talk to your health care provider about whether or not you should be tested. If you are having unprotected sex or discover that your partner is having unprotected sex with another person, you may want to ask your health care provider about being tested.

Where can I get more information?
If you have additional questions about syphilis, call the CDC National STD and AIDS Hotlines at 1-800-342-2437 or 1-800-227-8922. The hotlines are open 24 hours a day, seven days a week. For information in Spanish call 1-800-344-7432, 8:00 AM to 2:00 AM Eastern Time, seven days a week. For the Deaf and Hard of Hearing call 1-800-243-7889, 10:00 AM to 10:00 PM Eastern Time, Monday through Friday.

Find information about other STDs What is syphilis?
  • Syphilis is a curable infection caused by the bacteria Treponema pallidum.
  • The bacteria enter the body through mucous membranes or abraded skin.
  • Once inside the body, syphilis enters the blood stream and attaches to cells, damaging organs over time.
  • There are four stages through which untreated syphilis progresses, each stage with its own unique signs and symptoms:

  • - primary
    - secondary
    - latent
    - tertiary (or late)
How common is it?
  • Up until 2000, the reported rate of syphilis in the United States was at its lowest level since reporting began in 1941. In 2001, the number of cases reported increased slightly by a little over 2%.
  • This increase occurred only among men, while the number of cases continued to decline among women and among African American blacks.
  • Most of the reported syphilis cases are in the Southeast of the country, with a higher percentage of cases among African-Americans than whites. In 2001, the South had the highest rate of syphilis, accounting for 56% of reported cases in the US.
  • While rates appear to be improving, syphilis continues to disproportionately affect African Americans, with reported rates 16 times higher for African Americans than for white Americans.
  • Syphilis rates usually increase and decrease in seven-to-ten year cycles, which maybe one reason for the increase.
How can I get syphilis?
Sexual
  • Syphilis transmission can occur when infected lesions come in contact with the soft skin of the mucous membrane found inside the vagina, urethra or with an abrasion during vaginal, oral and anal sex, even if there is no sexual penetration.
  • It is most easily spread during the first stage because symptoms usually go unnoticed.
  • Syphilis can also be contracted from exposure to lesions or syphilitic "warts" during the secondary stage.
  • If "warts" are present, they may easily spread the syphilis bacteria, due to the large amount of virus present.
  • Because symptoms of secondary syphilis can recur, a person who has entered the latency stage of syphilis can still transmit the disease.
Nonsexual
  • Because syphilis bacteria are extremely fragile, they cannot be spread during contact with objects such as toilet seats or towels.
  • People, especially health care workers, can be at risk for syphilis if an abrasion or cut on the skin comes into contact with a syphilitic lesion Mother-to-Child
  • Syphilis can also be transmitted during pregnancy or during childbirth from a mother to her infant. What are the symptoms of syphilis?
Primary Syphilis
  • Chancre
    The primary stage of syphilis is usually marked by the appearance of a single sore, known as a chancre, within 10 to 90 days after contact with the bacteria at the site of infection. o It is usually appears as a single, painless sore, that is raised or elevated.
    - Chancres may be found:
    - outside the genitals, including the penis, scrotum and vagina
    - inside the vagina or rectum
    - at or around the anus
    - on the lips or in the mouth, though this is not as common.
    - The sore can last from one to five weeks and will go away by itself.
    - The chancre will go away with or without treatment. Without treatment, the person will still have syphilis and can transmit it to others.


  • The secondary stage of syphilis can develop 17 days to 6 1/2 months after infection.
  • Symptoms can last from 2 to 6 weeks.
  • Symptoms can include:
    - A rough, reddish-brown rash that appears on the palms of your hands or the soles of your feet, which normally does not itch. o Rashes on other parts of the body, including the neck, head and torso.
    - Condylomata lata or syphilitic "warts", moist, raised or elevated skin lesions, may be found in the anus or genital area. o "Mucous patches," flat, round, grayish-white sores, can appear on the mouth, throat, and cervix.
    - Patchy loss of hair on the head and other parts of the body.
  • Symptoms of secondary syphilis will clear up with or without treatment, but the disease will still be present if untreated. It will then enter into a latent
  • Latent syphilis is defined as the time where there are no signs or symptoms of the disease
  • Develops from two to 30+ years after infection.
  • Because there are no signs or symptoms, the only way to test for infection during the latent period is by blood test.
  • A relapse of secondary syphilis can occur once the disease has entered the latent stage. This normally will happen during the first two years of latency.
Late Stage (Tertiary)
  • Symptoms of late stage or tertiary syphilis can occur 2 to 30+ years after infection.
  • Complications during this stage can include:

  • - Gummas: Small bumps or tumors that can develop on the skin, bones, liver or any other organ.
    - Problems with heart and blood vessels
    - Chronic nervous system disorders, such as blindness, insanity and paralysis
  • If treated during this period, gummas will usually disappear. Though treatment at this phase will cure the disease and stop future damage to the body, it cannot repair or reverse the damage that occurred before treatment.
Congenital Syphilis
A mother infected with syphilis can pass the disease to her unborn child, either during pregnancy or in childbirth. A newborn infected in this manner has congenital syphilis.
  • Early signs generally appear from three to eight weeks after a baby is born.
  • Even though these symptoms develop soon after birth, most cases go unnoticed
  • Late congenital syphilis has similar symptoms to tertiary syphilis in adults, though heart complications rarely occur in cases of congenital syphilis.
How can I find out if I have syphilis?
Syphilis can be detected by blood tests, which looks for antibodies, or by testing fluid taken from lesions or swollen lymph nodes, which occur during primary or secondary syphilis. Tests on the lymphatic fluid or lesions look for antigens. Darkfield Exam
  • This test uses a fluid sample taken from the chancre during primary syphilis or from symptoms that occur during secondary syphilis found in areas such as the vagina (women) or the urethra (men).
  • The sample is then viewed under a microscope.
  • This test can only be done during primary or secondary syphilis, when sores, lesions & warts are present.
Blood Tests
  • There are two types of blood tests used to detect syphilis: nontreponemal and treponemal. These tests can be done in all stages of syphilis.
  • Nontreponemal blood tests are screening tests that look for certain antibodies , but not specifically syphilis antibodies. There are two types of screening test that may be used:
    - VDRL (Venereal Disease Research Laboratory)
    - or RPR (Rapid Plasma Reagent)
  • If the results for these test come back positive, a more specific treponemal blood test is performed to confirm a positive result. There are two types of confirmatory tests that may be used:
    - FTA-ABS (Fluorescent Treponemal Antibody Absorption Test)
  • There is a possibility of a false positive, particularly if the person tested has had syphilis before. A test may also be a false positive result if you are pregnant, have rheumatoid arthritis, use heroin, or have hepatitis, influenza or pneumonia.


Cerebrospinal Fluid Test
  • Another test uses cerebrospinal (involving the brain and spinal chord) fluid and is usually done if a person has damage to their central nervous system. Testing in Infants
  • If no signs and symptoms are found at birth, a blood test should be performed every 2 to 3 months on the infant until the test comes back negative. This is because an infant may test positive for syphilis and not be infected until the mother's antibodies, transmitted during pregnancy, clear the infant's body. For more information about testing and treatment of infants, talk with your health care provider, or visit your local health department. What is the treatment for syphilis?
  • The preferred treatment for syphilis is penicillin. If you are allergic to penicillin, your health care provider can suggest another antibiotic.
  • If you have HIV, tell your health care provider. The antibiotic may not be
  • Penicillin is the only recommended treatment for pregnant women. If you are pregnant and are allergic to penicillin, talk to your health care provider. He/she
  • Infants should be checked carefully at birth. Treatment can vary for many reasons. For more information about testing and treatment of infants, talk with your health care provider, or visit your local health department.
  • Take all medications as directed.
  • All partners should be examined and treated.
  • Do not have sex until you and your partner(s) have been treated and cured.
  • After treatment for primary or secondary syphilis, it is recommended that a person be retested after 6 months, and once again after a year.
  • If you are treated in the latent period, follow up tests are recommended
  • People who are infected with syphilis and also have HIV, should be retested every 3 months for 2 years.
What can I do to reduce my risk of getting syphilis?
  • Abstinence (not having sex).
  • Mutual monogamy (having sex with only one uninfected partner).
  • Latex condoms for vaginal and anal sex. Condoms may protect the penis or vagina from infection, but do not protect from contact with other areas such as the scrotum or anal area.
  • Several barrier methods can be used to reduce the risk of transmission of syphilis during oral sex. A non-lubricated condom can be used for mouth-to-penis contact. Household plastic wrap, a dental dam, or a latex condom cut-up and opened flat can reduce the risk of transmission during mouth-to-vulva/vagina or oral-anal (rimming) contact.
Why worry?
If you do not get treated, syphilis can cause blindness, paralysis, and problems with your bones and internal organs, including your heart.

Do I need to talk to my partner about syphilis?
Yes. Telling a partner can be hard, but keep in mind that some people with syphilis don't know they have it. It's important that you talk to your partner as soon as possible so she or he can get treatment. Also, it is possible to pass syphilis back and forth, so if you get treated and your partner doesn't, you may get infected again.

Should I talk to my health care provider about syphilis?
Yes. Because syphilis often does not have symptoms, you may need to talk to your health care provider about whether or not you should be tested. If you are having unprotected sex or discover that your partner is having unprotected sex with another person, you may want to ask your health care provider about being tested.

Where can I get more information?
If you have additional questions about syphilis, call the CDC National STD and AIDS Hotlines at 1-800-342-2437 or 1-800-227-8922. The hotlines are open 24 hours a day, seven days a week. For information in Spanish call 1-800-344-7432, 8:00 AM to 2:00 AM Eastern Time, seven days a week. For the Deaf and Hard of Hearing call 1-800-243-7889, 10:00 AM to 10:00 PM Eastern Time, Monday through Friday.

Find information about other STDs



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